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NARS antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O43776 |
| Other Accession | NM_004539, NP_004530 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Rat, Rabbit, Pig, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 60kDa |
| Gene ID | 4677 |
|---|---|
| Alias Symbol | ASNRS, NARS1 |
| Other Names | Asparagine--tRNA ligase, cytoplasmic, 6.1.1.22, Asparaginyl-tRNA synthetase, AsnRS, NARS |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-NARS antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | NARS antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NARS1 (HGNC:7643) |
|---|---|
| Function | Catalyzes the attachment of asparagine to tRNA(Asn) in a two- step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn) (PubMed:9421509, PubMed:32738225, PubMed:32788587). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells (PubMed:30171954, PubMed:12235211). Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells (PubMed:32788587). |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
References
Beaulande M.,et al.Nucleic Acids Res. 26:521-524(1998).
Shiba K.,et al.Nucleic Acids Res. 26:5045-5051(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Nusbaum C.,et al.Nature 437:551-555(2005).
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