|Other Accession||NM_005958, NP_005949|
|Reactivity||Human, Rabbit, Goat, Sheep, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Sheep, Bovine|
|Alias Symbol||MEL-1A-R, MT1|
|Other Names||Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor, MTNR1A|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-MTNR1A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MTNR1A antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus|
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Provided below are standard protocols that you may find useful for product applications.
Reppert S.M.,et al.Neuron 13:1177-1185(1994).
Ebisawa T.,et al.Biochem. Biophys. Res. Commun. 262:832-837(1999).
Huang Y.-H.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
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