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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   RBMX Antibody - C-terminal region   

RBMX Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - RBMX Antibody - C-terminal region AI14722

    Host: Rabbit
    Target Name: RBMX
    Sample Tissue: Jurkat Whole cell lysate
    Antibody Dilution: 1.0μg/mlRBMX is supported by BioGPS gene expression data to be expressed in Jurkat
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P38159
Other Accession NM_002139, NP_002130
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 42kDa
Additional Information
Gene ID 27316
Other Names RNA-binding motif protein, X chromosome, Glycoprotein p43, Heterogeneous nuclear ribonucleoprotein G, hnRNP G, RNA-binding motif protein, X chromosome, N-terminally processed, RBMX, HNRPG, RBMXP1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RBMX antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRBMX Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HNRPG, RBMXP1
Function RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue-specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter; may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the supraspliceosome complex that regulates pre-mRNA alternative splice site selection. Can either activate or suppress exon inclusion; acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN2. Represses the splicing of MAPT/Tau exon 10. Binds preferentially to single- stranded 5'-CC[A/C]-rich RNA sequence motifs localized in a single-stranded conformation; probably binds RNA as a homodimer. Binds non-specifically to pre-mRNAs. Plays also a role in the cytoplasmic TNFR1 trafficking pathways; promotes both the IL-1- beta-mediated inducible proteolytic cleavage of TNFR1 ectodomains and the release of TNFR1 exosome-like vesicles to the extracellular compartment.
Cellular Location Nucleus. Note=Component of ribonucleosomes Localizes in numerous small granules in the nucleus
Tissue Location Expressed strongly in oral keratinocytes, but only weakly detected in oral squamous cell carcinomas (at protein level).
Research Areas
Citations (0)

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Soulard M.,et al.Nucleic Acids Res. 21:4210-4217(1993).
Venables J.P.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Lingenfelter P.A.,et al.Mamm. Genome 12:538-545(2001).
Lin T.-Y.,et al.Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 293.00
Cat# AI14722
(40 western blots)
Availability: 2-3 days
Bulk Size
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