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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   SPC25 antibody - middle region   

SPC25 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - SPC25 antibody - middle region AI14729

    WB Suggested Anti-SPC25 Antibody Titration: 1.0 μg/ml
    Positive Control: 721_B Whole CellSPC25 is supported by BioGPS gene expression data to be expressed in 721_B
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9HBM1
Other Accession NM_020675, NP_065726
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 25kDa
Additional Information
Gene ID 57405
Alias Symbol AD024, MGC22228, SPBC25, hSpc25
Other Names Kinetochore protein Spc25, hSpc25, SPC25, SPBC25
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SPC25 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSPC25 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPC25
Synonyms SPBC25
Function Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
Cellular Location Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore
Research Areas
Citations (0)

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McCleland M.L.,et al.Curr. Biol. 14:131-137(2004).
Xiao H.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 293.00
Cat# AI14729
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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