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BPHL antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - BPHL antibody - N-terminal region AI14731

    WB Suggested Anti-BPHL Antibody Titration: 1.0 μg/ml
    Positive Control: THP-1 Whole Cell
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q86WA6
Other Accession NM_004332, NP_004323
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 30kDa
Additional Information
Gene ID 670
Alias Symbol BPH-RP, MCNAA, MGC125930, MGC41865, VACVASE
Other Names Valacyclovir hydrolase, VACVase, Valacyclovirase, 3.1.-.-, Biphenyl hydrolase-like protein, Biphenyl hydrolase-related protein, Bph-rp, Breast epithelial mucin-associated antigen, MCNAA, BPHL, MCNAA
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-BPHL antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsBPHL antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BPHL
Synonyms MCNAA
Function Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol.
Tissue Location Expressed at high levels in liver and kidney and lower levels in heart, intestine and skeletal muscle
Research Areas
Citations (0)
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References

Puente X.S.,et al.J. Biol. Chem. 270:12926-12932(1995).
Puente X.S.,et al.Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Larocca D.,et al.Cancer Res. 50:5925-5930(1990).

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$ 389.00
Cat# AI14731
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