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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HMGN3 antibody - middle region   

HMGN3 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - HMGN3 antibody - middle region AI14747

    WB Suggested Anti-HMGN3 Antibody Titration: 1.0 μg/ml
    Positive Control: 721_B Whole CellHMGN3 is supported by BioGPS gene expression data to be expressed in 721_B
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15651
Other Accession NM_001201362, NP_001188291
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 10kDa
Additional Information
Gene ID 9324
Alias Symbol DKFZp686E20226, PNAS-24, PNAS-25, TRIP7
Other Names High mobility group nucleosome-binding domain-containing protein 3, Thyroid receptor-interacting protein 7, TR-interacting protein 7, TRIP-7, HMGN3, TRIP7
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-HMGN3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHMGN3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HMGN3
Synonyms TRIP7
Function Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate and uterus. Low expression in liver, spleen, placenta and ovaries
Research Areas
Citations (0)

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Lee J.W.,et al.Mol. Endocrinol. 9:243-254(1995).
Leong P.W.,et al.Virology 295:147-159(2002).
Yu W.-Q.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Go V.S.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 293.00
Cat# AI14747
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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