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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PPP1R3B antibody - N-terminal region   

PPP1R3B antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - PPP1R3B antibody - N-terminal region AI14750

    WB Suggested Anti-PPP1R3B Antibody Titration: 1.0 μg/ml
    Positive Control: MCF7 Whole Cell
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86XI6
Other Accession NM_024607, NP_078883
Reactivity Human, Mouse, Rat, Rabbit, Goat, Horse, Bovine, Guinea Pig, Dog
Predicted Rabbit, Goat, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 31kDa
Additional Information
Gene ID 79660
Alias Symbol FLJ14005, FLJ34675, GL, PPP1R4, PTG
Other Names Protein phosphatase 1 regulatory subunit 3B, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, Protein phosphatase 1 regulatory subunit 4, PP1 subunit R4, Protein phosphatase 1 subunit GL, PTG, PPP1R3B, PPP1R4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PPP1R3B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPPP1R3B antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP1R3B
Synonyms PPP1R4
Function Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity).
Tissue Location Highly expressed in the liver and, at lower levels, in skeletal muscle, including in vastus lateralis, gastrocnemius and soleus (at protein level). Highest mRNA levels are observed in skeletal muscle, and only moderate levels in liver and heart. Weak expression in placenta and lung
Research Areas
Citations (0)

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Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Munro S.,et al.Diabetes 51:591-598(2002).
Montori-Grau M.,et al.Biochem. J. 405:107-113(2007).

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$ 293.00
Cat# AI14750
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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