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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ENTPD5 antibody - N-terminal region   

ENTPD5 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - ENTPD5 antibody - N-terminal region AI14762

    WB Suggested Anti-ENTPD5 Antibody Titration: 1.0 μg/ml
    Positive Control: HT1080 Whole Cell
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75356
Other Accession NM_001249, NP_001240
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 47kDa
Additional Information
Gene ID 957
Alias Symbol CD39L4, MGC163357, MGC163359, NTPDase-5, PCPH
Other Names Ectonucleoside triphosphate diphosphohydrolase 5, NTPDase 5,, CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, GDPase ENTPD5,, Nucleoside diphosphatase, Uridine-diphosphatase ENTPD5, UDPase ENTPD5, ENTPD5, CD39L4, PCPH
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ENTPD5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsENTPD5 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD39L4, PCPH
Function Uridine diphosphatase (UDPase) that promotes protein N- glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
Cellular Location Endoplasmic reticulum. Secreted
Tissue Location Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues
Research Areas
Citations (0)

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Chadwick B.P.,et al.Genomics 50:357-367(1998).
Recio J.A.,et al.Mol. Carcinog. 27:229-236(2000).
Murphy-Piedmonte D.M.,et al.Biochim. Biophys. Acta 1747:251-259(2005).
Heilig R.,et al.Nature 421:601-607(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 293.00
Cat# AI14762
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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