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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Pacsin3 antibody - C-terminal region   

Pacsin3 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Pacsin3 antibody - C-terminal region AI14771

    WB Suggested Anti-Pacsin3 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Heart
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99JB8
Other Accession NM_028733, NP_083009
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Additional Information
Gene ID 80708
Alias Symbol 4921507A02Rik, 6330413E15Rik, AW413130
Other Names Protein kinase C and casein kinase II substrate protein 3, Pacsin3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Pacsin3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPacsin3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pacsin3
Function Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
Cellular Location Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Detected at the inner aspect of the plasma membrane in myotubes
Tissue Location Highly expressed in skeletal muscle, heart and lung; also detected in brain, kidney and uterus (at protein level).
Research Areas
Citations (0)

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Modregger J.,et al.J. Cell Sci. 113:4511-4521(2000).
Sumoy L.,et al.Gene 262:199-205(2001).
Cuajungco M.P.,et al.J. Biol. Chem. 281:18753-18762(2006).
Roach W.,et al.Biochem. Biophys. Res. Commun. 355:745-750(2007).
Villen J.,et al.Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).

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$ 293.00
Cat# AI14771
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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