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Pacsin3 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q99JB8 |
| Other Accession | NM_028733, NP_083009 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 48kDa |
| Gene ID | 80708 |
|---|---|
| Alias Symbol | 4921507A02Rik, 6330413E15Rik, AW413130 |
| Other Names | Protein kinase C and casein kinase II substrate protein 3, Pacsin3 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Pacsin3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Pacsin3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Pacsin3 |
|---|---|
| Function | Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity. |
| Cellular Location | Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Detected at the inner aspect of the plasma membrane in myotubes |
| Tissue Location | Highly expressed in skeletal muscle, heart and lung; also detected in brain, kidney and uterus (at protein level) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Modregger J.,et al.J. Cell Sci. 113:4511-4521(2000).
Sumoy L.,et al.Gene 262:199-205(2001).
Cuajungco M.P.,et al.J. Biol. Chem. 281:18753-18762(2006).
Roach W.,et al.Biochem. Biophys. Res. Commun. 355:745-750(2007).
Villen J.,et al.Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
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