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UACA antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - UACA antibody - C-terminal region AI14773

    WB Suggested Anti-UACA Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Lung
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9BZF9
Other Accession NM_001008224, NP_001008225
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 154kDa
Additional Information
Gene ID 55075
Alias Symbol FLJ10128, KIAA1561, MGC141967, MGC141969, NUCLING
Other Names Uveal autoantigen with coiled-coil domains and ankyrin repeats, UACA, KIAA1561
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-UACA antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsUACA antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UACA
Synonyms KIAA1561
Function Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).
Cellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Expressed diffusely in cytoplasm
Tissue Location Highly expressed in skeletal muscle, heart, kidney and pancreas. Expressed in choroid, retina and epidermal melanocytes Expressed in eye muscles and thyroid follicular cells
Research Areas
Citations (0)
citation

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References

Yamada K.,et al.Biochem. Biophys. Res. Commun. 280:1169-1176(2001).
Nagase T.,et al.DNA Res. 7:273-281(2000).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Zody M.C.,et al.Nature 440:671-675(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 389.00
Cat# AI14773
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