|Other Accession||NM_004288, NP_004279|
|Reactivity||Human, Mouse, Rat, Pig, Guinea Pig|
|Predicted||Human, Mouse, Rat|
|Alias Symbol||B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP|
|Other Names||Cytohesin-interacting protein, Cytohesin binder and regulator, CYBR, Cytohesin-associated scaffolding protein, CASP, Cytohesin-binding protein HE, Cbp HE, Pleckstrin homology Sec7 and coiled-coil domains-binding protein, CYTIP, PSCDBP|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CYTIP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CYTIP antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.|
|Cellular Location||Cytoplasm. Early endosome. Note=Recruited from the cytosol to endosomes by SNX27|
|Tissue Location||Expressed in lymph nodes, thymus, spleen, lung, peripheral blood leukocytes and bone marrow|
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Provided below are standard protocols that you may find useful for product applications.
Tang P.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:2625-2629(2002).
Boehm T.,et al.EMBO J. 22:1014-1024(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Dixon B.,et al.Biochim. Biophys. Acta 1216:321-324(1993).
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