LIMCH1 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9UPQ0 |
Other Accession | NM_014988, NP_055803 |
Reactivity | Human, Mouse, Rat, Rabbit, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 121kDa |
Gene ID | 22998 |
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Alias Symbol | DKFZp434I0312, DKFZp686A01247, DKFZp686B2470, DKFZp686G18243, DKFZp686G2094, DKFZp781C1754, DKFZp781I1455, LIMCH1A, LMO7B, MGC72127 |
Other Names | LIM and calponin homology domains-containing protein 1, LIMCH1, KIAA1102 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-LIMCH1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | LIMCH1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LIMCH1 (HGNC:29191) |
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Function | Actin stress fibers-associated protein that activates non- muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. |
Cellular Location | Cytoplasm, cytoskeleton, stress fiber |
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Provided below are standard protocols that you may find useful for product applications.
References
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Hillier L.W.,et al.Nature 434:724-731(2005).
Olsen J.V.,et al.Cell 127:635-648(2006).
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