|Other Accession||NM_018170, NP_060640|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Rat, Rabbit, Chicken, Horse, Guinea Pig, Dog|
|Alias Symbol||FLJ10656, HsT3101, MGC19513, P15RS|
|Other Names||Regulation of nuclear pre-mRNA domain-containing protein 1A, Cyclin-dependent kinase inhibitor 2B-related protein, p15INK4B-related protein, RPRD1A, P15RS|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RPRD1A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RPRD1A antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.|
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Provided below are standard protocols that you may find useful for product applications.
Liu J.,et al.Biochem. Biophys. Res. Commun. 299:880-885(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (JAN-2010) to UniProtKB.
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
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