|Other Accession||NM_183352, NP_899195|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||D3S1231E, SEC13L1, SEC13R, npp-20|
|Other Names||Protein SEC13 homolog, SEC13-like protein 1, SEC13-related protein, SEC13, D3S1231E, SEC13L1, SEC13R|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-SEC13 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SEC13 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||D3S1231E, SEC13L1, SEC13R|
|Function||Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway.|
|Cellular Location||Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note=In interphase, localizes at both sides of the NPC|
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Provided below are standard protocols that you may find useful for product applications.
Swaroop A.,et al.Hum. Mol. Genet. 3:1281-1286(1994).
Yu W.,et al.Genome Res. 7:353-358(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
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