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>   home   >   Products   >   Primary Antibodies   >   SNRPE antibody - N-terminal region   

SNRPE antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - SNRPE antibody - N-terminal region AI14930

    WB Suggested Anti-SNRPE Antibody Titration: 1.0 μg/ml
    Positive Control: 721_B Whole CellSNRPE is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P62304
Other Accession NM_003094, NP_003085
Reactivity Human, Mouse, Rat, Bovine, Guinea Pig, Dog
Predicted Mouse, Rat, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 10kDa
Additional Information
Gene ID 6635
Alias Symbol B-raf, SME, Sm-E
Other Names Small nuclear ribonucleoprotein E, snRNP-E, Sm protein E, Sm-E, SmE, SNRPE
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SNRPE antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSNRPE antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.
Cellular Location Cytoplasm, cytosol. Nucleus. Note=SMN- mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes
Tissue Location Widely expressed. In scalp skin, it is present in the hair follicle, the epidermis, and the dermis
Citations (0)

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Stanford D.R.,et al.Nucleic Acids Res. 16:10593-10605(1988).
Stanford D.R.,et al.J. Biol. Chem. 263:17772-17779(1988).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Stanford D.R.,et al.J. Biol. Chem. 262:9931-9934(1987).

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$ 293.00
Cat# AI14930
(40 western blots)
Availability: 2-3 days
Bulk Size
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