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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   DPP4 antibody - N-terminal region   

DPP4 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - DPP4 antibody - N-terminal region AI14942

    WB Suggested Anti-DPP4 Antibody Titration: 1.0 μg/ml
    Positive Control: HCT15 Whole Cell
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P27487
Other Accession NM_001935, NP_001926
Reactivity Human, Rat, Pig, Horse, Dog
Predicted Human, Pig, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 84kDa
Additional Information
Gene ID 1803
Alias Symbol ADABP, ADCP2, CD26, DPPIV, TP103
Other Names Dipeptidyl peptidase 4,, ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, CD26, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV soluble form, DPP4, ADCP2, CD26
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-DPP4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsDPP4 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DPP4
Synonyms ADCP2, CD26
Function Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF- kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Cellular Location Dipeptidyl peptidase 4 soluble form: Secreted. Note=Detected in the serum and the seminal fluid
Tissue Location Expressed specifically in lymphatic vessels but not in blood vessels in the skin, small intestine, esophagus, ovary, breast and prostate glands. Not detected in lymphatic vessels in the lung, kidney, uterus, liver and stomach (at protein level). Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon.
Research Areas
Citations (0)

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Misumi Y.,et al.Biochim. Biophys. Acta 1131:333-336(1992).
Darmoul D.,et al.J. Biol. Chem. 267:4824-4833(1992).
Tanaka T.,et al.J. Immunol. 149:481-486(1992).
Tanaka T.,et al.J. Immunol. 150:2090-2090(1993).
Abbott C.A.,et al.Immunogenetics 40:331-338(1994).

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$ 293.00
Cat# AI14942
(40 western blots)
Availability: 2-3 days
Bulk Size
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