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CNR2 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - CNR2 antibody - C-terminal region AI14969

    WB Suggested Anti-CNR2 Antibody Titration: 1.0 μg/ml
    Positive Control: 721_B Whole CellCNR2 is supported by BioGPS gene expression data to be expressed in 721_B
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P34972
Other Accession NM_001841, NP_001832
Reactivity Human, Mouse, Rat, Horse
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 40kDa
Additional Information
Gene ID 1269
Alias Symbol CB2, CX5
Other Names Cannabinoid receptor 2, CB-2, CB2, hCB2, CX5, CNR2, CB2A, CB2B
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CNR2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCNR2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNR2
Synonyms CB2A, CB2B
Function Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Perikaryon Note=Localizes to apical dendrite of pyramidal neurons
Tissue Location Preferentially expressed in cells of the immune system with higher expression in B-cells and NK cells (at protein level). Expressed in skin in suprabasal layers and hair follicles (at protein level). Highly expressed in tonsil and to a lower extent in spleen, peripheral blood mononuclear cells, and thymus. PubMed:14657172 could not detect expression in normal brain. Expressed in brain by perivascular microglial cells and dorsal root ganglion sensory neurons (at protein level). Two isoforms are produced by alternative promoter usage and differ only in the 5' UTR: isoform CB2A is observed predominantly in testis with some expression in brain, while isoform CB2B is predominant in spleen and leukocytes
Research Areas
Citations (0)

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Munro S.,et al.Nature 365:61-65(1993).
Liu Q.-R.,et al.Genes Brain Behav. 8:519-530(2009).
Bruess M.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Warren C.N.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Saravanan T.,et al.Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.

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$ 293.00
Cat# AI14969
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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