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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CD207 antibody - C-terminal region   

CD207 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - CD207 antibody - C-terminal region AI14970

    Host: Rabbit
    Target Name: CD207
    Sample Tissue: Fetal Kidney
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UJ71
Other Accession NM_015717, NP_056532
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig
Predicted Mouse, Rat, Pig, Horse, Bovine, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 36kDa
Additional Information
Gene ID 50489
Alias Symbol CLEC4K
Other Names C-type lectin domain family 4 member K, Langerin, CD207, CD207, CLEC4K
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CD207 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCD207 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD207
Synonyms CLEC4K
Function Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
Cellular Location Membrane; Single-pass type II membrane protein. Note=Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes
Tissue Location Exclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.
Research Areas
Citations (0)

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Valladeau J.,et al.Immunity 12:71-81(2000).
Hillier L.W.,et al.Nature 434:724-731(2005).
Stambach N.S.,et al.Glycobiology 13:401-410(2003).
Valladeau J.,et al.Immunol. Res. 28:93-107(2003).
de Witte L.,et al.Nat. Med. 13:367-371(2007).

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$ 293.00
Cat# AI14970
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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