|Other Accession||NM_138715, NP_619729|
|Reactivity||Human, Pig, Horse, Bovine, Dog|
|Alias Symbol||CD204, SCARA1, SR-A, phSR1, phSR2, SRA|
|Other Names||Macrophage scavenger receptor types I and II, Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD204, MSR1, SCARA1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-MSR1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MSR1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL) (PubMed:2251254). Isoform III does not internalize acetylated LDL (PubMed:9548586).|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Matsumoto A.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:9133-9137(1990).
Gough P.J.,et al.J. Lipid Res. 39:531-543(1998).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Emi M.,et al.J. Biol. Chem. 268:2120-2125(1993).
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