|Other Accession||NM_138715, NP_619729|
|Reactivity||Human, Pig, Horse, Bovine, Dog|
|Alias Symbol||CD204, SCARA1, SR-A, phSR1, phSR2, SRA|
|Other Names||Macrophage scavenger receptor types I and II, Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD204, MSR1, SCARA1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-MSR1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MSR1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL) (PubMed:2251254). Isoform III does not internalize acetylated LDL (PubMed:9548586).|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Matsumoto A.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:9133-9137(1990).
Gough P.J.,et al.J. Lipid Res. 39:531-543(1998).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Emi M.,et al.J. Biol. Chem. 268:2120-2125(1993).
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