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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PAG1 antibody - C-terminal region   

PAG1 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - PAG1 antibody - C-terminal region AI15019

    WB Suggested Anti-PAG1 Antibody Titration: 1.0 μg/ml
    Positive Control: 721_B Whole Cell
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NWQ8
Other Accession NM_018440, NP_060910
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 47kDa
Additional Information
Gene ID 55824
Alias Symbol CBP, FLJ37858, MGC138364, PAG
Other Names Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Csk-binding protein, Transmembrane adapter protein PAG, Transmembrane phosphoprotein Cbp, PAG1, CBP, PAG
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PAG1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPAG1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAG1
Synonyms CBP, PAG
Function Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Cellular Location Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts
Tissue Location Ubiquitously expressed. Present in germinal center B-cells, plasma cells, T-cells, monocytes and platelets (at protein level).
Research Areas
Citations (0)

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Brdicka T.,et al.J. Exp. Med. 191:1591-1604(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Brdickova N.,et al.FEBS Lett. 507:133-136(2001).
Brill L.M.,et al.Anal. Chem. 76:2763-2772(2004).

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$ 293.00
Cat# AI15019
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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