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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   QKI antibody - N-terminal region   

QKI antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - QKI antibody - N-terminal region AI15031

    WB Suggested Anti-QKI Antibody Titration: 1.0 μg/ml
    Positive Control: Hela Whole CellThere is BioGPS gene expression data showing that QKI is expressed in HeLa
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96PU8
Other Accession NM_206853, NP_996735
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 35kDa
Additional Information
Gene ID 9444
Alias Symbol DKFZp586I0923, Hqk, QK, QK1, QK3, hqkI
Other Names Protein quaking, Hqk, HqkI, QKI, HKQ
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-QKI antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsQKI antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name QKI
Synonyms HKQ
Function RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).
Cellular Location Nucleus. Cytoplasm
Tissue Location Expressed in the frontal cortex of brain. Down-regulated in the brain of schizophrenic patients
Research Areas
Citations (0)

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Li Z.Z.,et al.Jpn. J. Cancer Res. 93:167-177(2002).
Xia J.-H.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
Li H.,et al.Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 293.00
Cat# AI15031
(40 western blots)
Availability: 2-3 days
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