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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MARCKSL1 antibody - C-terminal region   

MARCKSL1 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - MARCKSL1 antibody - C-terminal region AI15076

    WB Suggested Anti-MARCKSL1 Antibody Titration: 1.0 μg/ml
    Positive Control: 293T Whole CellMARCKSL1 is supported by BioGPS gene expression data to be expressed in HEK293T
  • WB - MARCKSL1 antibody - C-terminal region AI15076

    Target Name:MARCKSL1
    Sample Tissue:Human Fetal Lung
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49006
Other Accession NM_023009, NP_075385
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Predicted Mouse, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 19kDa
Additional Information
Gene ID 65108
Alias Symbol F52, MACMARCKS, MLP, MLP1, MRP
Other Names MARCKS-related protein, MARCKS-like protein 1, Macrophage myristoylated alanine-rich C kinase substrate, Mac-MARCKS, MacMARCKS, MARCKSL1, MLP, MRP
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-MARCKSL1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMARCKSL1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MLP, MRP
Function Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity).
Cellular Location Cytoplasm. Cell membrane. Note=Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin (By similarity) In prostate cancers, detected in the cytoplasm and associated with apical or basal membranes (By similarity).
Research Areas
Citations (0)

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Blockx H.,et al.Submitted (FEB-1993) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Olsen J.V.,et al.Cell 127:635-648(2006).

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$ 293.00
Cat# AI15076
(40 western blots)
Availability: 2-3 days
Bulk Size
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