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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SPAM1 Antibody - middle region   

SPAM1 Antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - SPAM1 Antibody - middle region AI15082

    Host: Rabbit
    Target Name: SPAM1
    Sample Tissue: 786-0 Whole Cell lysates
    Antibody Dilution: 1.0μg/ml
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P38567
Other Accession NP_694859
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 55kDa
Additional Information
Gene ID 6677
Alias Symbol SPAM1, HYAL3, PH20,
Other Names Hyaluronidase PH-20, Hyal-PH20, 3.2.1.35, Hyaluronoglucosaminidase PH-20, Sperm adhesion molecule 1, Sperm surface protein PH-20, SPAM1, HYAL3, PH20
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-SPAM1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSPAM1 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPAM1
Synonyms HYAL3, PH20
Function Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Location Testis..
Research Areas
Citations (0)

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References

Lin Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:10071-10075(1993).
Gmachl M.,et al.FEBS Lett. 336:545-548(1993).
Jones M.H.,et al.Genomics 29:796-800(1995).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).

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$ 293.00
Cat# AI15082
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