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SPAM1 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P38567 |
| Other Accession | NP_694859 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 55kDa |
| Gene ID | 6677 |
|---|---|
| Alias Symbol | SPAM1, HYAL3, PH20, |
| Other Names | Hyaluronidase PH-20, Hyal-PH20, 3.2.1.35, Hyaluronoglucosaminidase PH-20, Sperm adhesion molecule 1, Sperm surface protein PH-20, SPAM1, HYAL3, PH20 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-SPAM1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SPAM1 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SPAM1 |
|---|---|
| Synonyms | HYAL3, PH20 |
| Function | Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid. |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
| Tissue Location | Testis.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Lin Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:10071-10075(1993).
Gmachl M.,et al.FEBS Lett. 336:545-548(1993).
Jones M.H.,et al.Genomics 29:796-800(1995).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).
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