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ITGA2 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • IF - ITGA2 Antibody - C-terminal region AI15087
    Sample Type : HeLa cells
    Primary Antibody Dilution : 1:150
    Secondary Antibody : Goat anti-rabbit-Alexa Fluor 488 Secondary Antibody Dilution : 1:800 Color/Signal Descriptions : Green: ITGA2Blue: DAPI
    Gene Name : ITGA2 Submitted by : COCOLA Cinzia, Stem Cell Biology and Cancer Research Unit
    detail
  • WB - ITGA2 Antibody - C-terminal region AI15087

    WB Suggested Anti-ITGA2 Antibody Titration: 1.0 μg/ml
    Positive Control: HT1080 Whole CellITGA2 is supported by BioGPS gene expression data to be expressed in HT1080
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF
Primary Accession P17301
Other Accession NM_002203, NP_002194
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 126kDa
Additional Information
Gene ID 3673
Alias Symbol BR, CD49B, GPIa, VLA-2, VLAA2, BDPLT9
Other Names Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b, ITGA2, CD49B
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ITGA2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsITGA2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ITGA2
Synonyms CD49B
Function Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8.
Cellular Location Membrane; Single-pass type I membrane protein.
Research Areas
Citations (0)
citation

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References

Takada Y.,et al.J. Cell Biol. 109:397-407(1989).
Schmutz J.,et al.Nature 431:268-274(2004).
Zutter M.M.,et al.J. Biol. Chem. 269:463-469(1994).
Bergelson J.M.,et al.J. Virol. 67:6847-6852(1993).
Graham K.L.,et al.J. Virol. 77:9969-9978(2003).

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$ 389.00
Cat# AI15087
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