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RAP2B antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - RAP2B antibody - C-terminal region AI15096

    WB Suggested Anti-RAP2B Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Liver
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P61225
Other Accession NM_002886, NP_002877
Reactivity Human, Mouse, Rat, Rabbit, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Yeast, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 20kDa
Additional Information
Gene ID 5912
Alias Symbol MGC20484
Other Names Ras-related protein Rap-2b, RAP2B
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RAP2B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRAP2B antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAP2B
Function Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.
Cellular Location Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Note=Associated with red blood cells- released vesicles
Tissue Location Expressed in red blood cells (at protein level).
Research Areas
Citations (0)
citation

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References

Farrell F.X.,et al.Nucleic Acids Res. 18:4281-4281(1990).
Ohmstede C.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:6527-6531(1990).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Farrell F.X.,et al.Biochem. J. 289:349-355(1993).
Evellin S.,et al.J. Biol. Chem. 277:16805-16813(2002).

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$ 389.00
Cat# AI15096
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