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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GPR68 Antibody - middle region   

GPR68 Antibody - middle region

Rabbit Polyclonal Antibody

  • WB - GPR68 Antibody - middle region AI15103

    WB Suggested Anti-GPR68 Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15743
Other Accession NM_003485, NP_003476
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 41kDa
Additional Information
Gene ID 8111
Alias Symbol MGC111379, MGC156983, OGR1, GPR12A
Other Names Ovarian cancer G-protein coupled receptor 1, OGR-1, G-protein coupled receptor 68, GPR12A, Sphingosylphosphorylcholine receptor, GPR68, OGR1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-GPR68 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGPR68 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPR68
Synonyms OGR1
Function Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system.
Research Areas
Citations (0)

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An S.,et al.FEBS Lett. 375:121-124(1995).
Xu Y.,et al.Genomics 35:397-402(1996).
Kaighin V.A.,et al.Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
King M.M.,et al.Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
Heilig R.,et al.Nature 421:601-607(2003).

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$ 293.00
Cat# AI15103
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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