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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   GPR37 Antibody - C-terminal region   

GPR37 Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - GPR37 Antibody - C-terminal region AI15109

    WB Suggested Anti-GPR37 Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Heart
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15354
Other Accession NM_005302, NP_005293
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 64kDa
Additional Information
Gene ID 2861
Alias Symbol EDNRBL, PAELR, hET(B)R-LP
Other Names Prosaposin receptor GPR37, Endothelin B receptor-like protein 1, ETBR-LP-1, G-protein coupled receptor 37, Parkin-associated endothelin receptor-like receptor, PAELR, GPR37
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-GPR37 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGPR37 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPR37
Function Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.
Cellular Location Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).
Research Areas
Citations (0)

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Marazziti D.,et al.Genomics 45:68-77(1997).
Donohue P.J.,et al.Brain Res. Mol. Brain Res. 54:152-160(1998).
Zeng Z.,et al.Biochem. Biophys. Res. Commun. 233:559-567(1997).
Imai Y.,et al.Cell 105:891-902(2001).
Hillier L.W.,et al.Nature 424:157-164(2003).

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$ 293.00
Cat# AI15109
(40 western blots)
Availability: 2-3 days
Bulk Size
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