CCNO antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P22674 |
Other Accession | NM_021147, NP_066970 |
Reactivity | Human, Mouse, Rabbit, Pig, Horse |
Predicted | Human, Mouse, Rabbit, Pig, Horse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 38kDa |
Gene ID | 10309 |
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Alias Symbol | CCNU, FLJ22422, UDG2, UNG2 |
Other Names | Cyclin-O, CCNO |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CCNO antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | CCNO antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCNO (HGNC:18576) |
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Function | Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking. |
Cellular Location | Cytoplasm. Nucleus, nucleolus Note=Localizes to the apical part of cytoplasm |
Tissue Location | Present in respiratory cells (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
References
Muller S.J.,et al.Biochim. Biophys. Acta 1088:197-207(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Muller S.J.,et al.J. Biol. Chem. 268:1310-1319(1993).
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