|Other Accession||NM_005296, NP_005287|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Alias Symbol||GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9|
|Other Names||Lysophosphatidic acid receptor 4, LPA receptor 4, LPA-4, G-protein coupled receptor 23, P2Y purinoceptor 9, P2Y9, P2Y5-like receptor, Purinergic receptor 9, LPAR4, GPR23, LPA4, P2RY9|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LPAR4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LPAR4 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GPR23, LPA4, P2RY9|
|Function||Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||High expression in ovary. Not detected in the brain regions thalamus, putamen, caudate, frontal cortex, pons, hypothalamus and hippocampus.|
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Provided below are standard protocols that you may find useful for product applications.
O'Dowd B.F.,et al.Gene 187:75-81(1997).
Bohm S.K.,et al.Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
Janssens R.,et al.Biochem. Biophys. Res. Commun. 236:106-112(1997).
Kopatz S.A.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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