|Other Accession||NM_181885, NP_871001|
|Alias Symbol||GPCR142, GPR100, MGC126556, MGC126558, RLN3R2, RXFPR4|
|Other Names||Relaxin-3 receptor 2, RLN3 receptor 2, G-protein coupled receptor 100, G-protein coupled receptor GPCR142, Insulin-like peptide INSL5 receptor, Relaxin family peptide receptor 4, RXFP4, GPR100, RLN3R2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RXFP4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RXFP4 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon.|
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Provided below are standard protocols that you may find useful for product applications.
Liu C.,et al.J. Biol. Chem. 278:50765-50770(2003).
Fredriksson R.,et al.FEBS Lett. 554:381-388(2003).
Boels K.,et al.Br. J. Pharmacol. 140:932-938(2003).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Takeda S.,et al.FEBS Lett. 520:97-101(2002).
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