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SLC22A9 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - SLC22A9 antibody - C-terminal region AI15192

    WB Suggested Anti-SLC22A9 Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Heart
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8IVM8
Other Accession NM_080866, NP_543142
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 62kDa
Additional Information
Gene ID 114571
Alias Symbol FLJ23666, HOAT4, OAT4, OAT7, UST3H, ust3
Other Names Solute carrier family 22 member 9, Organic anion transporter 7, SLC22A9, hOAT4, OAT7, UST3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SLC22A9 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSLC22A9 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC22A9
Synonyms hOAT4, OAT7, UST3
Function Sodium-independent organic anion transporter, exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones such as estrone 3-sulfate (E1S) and dehydroepiandrosterone sulfate (DHEAS) (PubMed:17393504, PubMed:26239079, PubMed:28945155). Can transport the statin pravastatin and may contribute to its disposition into the hepatocytes when the function of OATPs is compromised (PubMed:26239079). It is specifically activated by 3 to 5 carbons- containing short-chain fatty acids/SCFAs, including propionate (propanoate), butyrate (butanoate) and valerate (pentanoate) (PubMed:17393504). May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs, in particular butanoate, at the sinusoidal membrane of hepatocytes (PubMed:17393504).
Cellular Location Basolateral cell membrane; Multi-pass membrane protein. Note=Enriched at the sinusoidal part of the plasma membrane
Tissue Location Specifically expressed in liver (also at protein level).
Research Areas
Citations (0)
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References

Shin H.J.,et al.Hepatology 45:1046-1055(2007).
Engel K.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Takanaga H.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Guo J.H.,et al.Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 389.00
Cat# AI15192
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