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FCER2 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - FCER2 Antibody - C-terminal region AI15200

    Host: Rabbit
    Target Name: FCER2
    Sample Tissue: Fetal Kidney lysates
    Antibody Dilution: 1.0μg/ml
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P06734
Other Accession NM_002002, NP_001993
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 35kDa
Additional Information
Gene ID 2208
Alias Symbol CD23, CD23A, CLEC4J, FCE2, IGEBF
Other Names Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2, CD23A, CLEC4J, FCE2, IGEBF
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-FCER2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFCER2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FCER2
Synonyms CD23A, CLEC4J, FCE2, IGEBF
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells (PubMed:2167225). On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine- nitric oxide pathway (PubMed:7544003).
Cellular Location Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Note=Also exists as a soluble excreted form, sCD23
Tissue Location Detected in urine (at protein level).
Research Areas
Citations (0)
citation

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References

Ikuta K.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:819-823(1987).
Kikutani H.,et al.Cell 47:657-665(1986).
Luedin C.,et al.EMBO J. 6:109-114(1987).
Grimwood J.,et al.Nature 428:529-535(2004).
Yokota A.,et al.Cell 55:611-618(1988).

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$ 389.00
Cat# AI15200
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