|Other Accession||NM_006865, NP_006856|
|Alias Symbol||CD85E, HM31, HM43, ILT6, LIR-4, LIR4, e3|
|Other Names||Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4, Monocyte inhibitory receptor HM43/HM31, CD85e, LILRA3, ILT6, LIR4|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LILRA3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LILRA3 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS- induced TNF-alpha production by monocytes.|
|Tissue Location||Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung.|
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Provided below are standard protocols that you may find useful for product applications.
Arm J.P.,et al.J. Immunol. 159:2342-2349(1997).
Borges L.,et al.J. Immunol. 159:5192-5196(1997).
Samaridis J.,et al.Eur. J. Immunol. 27:660-665(1997).
Grimwood J.,et al.Nature 428:529-535(2004).
Norman P.J.,et al.Immunogenetics 55:165-171(2003).
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