|Other Accession||NM_145431, NP_663406|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||AL022765, BC018399, Nle|
|Other Names||Notchless protein homolog 1, Nle1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Nle1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Nle1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in regulating Notch activity (Probable). Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival.|
|Cellular Location||Nucleus, nucleolus.|
|Tissue Location||Highest expression in heart, brain, lung, liver, skeletal muscle and testis with lower levels in spleen and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Cormier S.,et al.Mol. Cell. Biol. 26:3541-3549(2006).
Lossie A.C.,et al.BMC Genet. 13:106-106(2012).
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