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IL22RA2 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - IL22RA2 Antibody - C-terminal region AI15246

    WB Suggested Anti-IL22RA2 Antibody Titration: 1.0 μg/ml
    Positive Control: RPMI-8226 Whole Cell
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q969J5
Other Accession NM_052962, NP_443194
Reactivity Human, Dog
Predicted Human, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 26kDa
Additional Information
Gene ID 116379
Alias Symbol CRF2-10, CRF2-S1, CRF2X, IL-22BP, MGC150509, MGC150510
Other Names Interleukin-22 receptor subunit alpha-2, IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1, Interleukin-22-binding protein, IL-22BP, IL22BP, ZcytoR16, IL22RA2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-IL22RA2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsIL22RA2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL22RA2
Function Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
Cellular Location Secreted.
Tissue Location Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach
Research Areas
Citations (0)
citation

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References

Gruenberg B.H.,et al.Genes Immun. 2:329-334(2001).
Kotenko S.V.,et al.J. Immunol. 166:7096-7103(2001).
Dumoutier L.,et al.J. Immunol. 166:7090-7095(2001).
Xu W.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:9511-9516(2001).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).

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$ 389.00
Cat# AI15246
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