|Other Accession||NM_003006, NP_002997|
|Reactivity||Human, Rat, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rat, Pig, Bovine, Guinea Pig, Dog|
|Alias Symbol||CD162, CLA, PSGL-1, PSGL1|
|Other Names||P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-SELPLG antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SELPLG Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed on neutrophils, monocytes and most lymphocytes|
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Provided below are standard protocols that you may find useful for product applications.
Veldman G.M.,et al.J. Biol. Chem. 270:16470-16475(1995).
Sako D.,et al.Cell 75:1179-1186(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Moore K.L.,et al.J. Biol. Chem. 269:23318-23327(1994).
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