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>   home   >   Products   >   Primary Antibodies   >   CEP135 Antibody - N-terminal region   

CEP135 Antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - CEP135 Antibody - N-terminal region AI15251

    WB Suggested Anti-CEP135 Antibody Titration: 1.0 μg/ml
    Positive Control: A549 Whole Cell
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q66GS9
Other Accession NM_025009, NP_079285
Reactivity Human, Rabbit, Pig, Horse, Bovine, Dog
Predicted Human, Rabbit, Pig, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 133kDa
Additional Information
Gene ID 9662
Alias Symbol CEP4, KIAA0635
Other Names Centrosomal protein of 135 kDa, Cep135, Centrosomal protein 4, CEP135, CEP4, KIAA0635
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CEP135 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCEP135 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CEP135
Synonyms CEP4, KIAA0635
Function Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP and CEP290 and recruitment of WRAP73 to centrioles. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles
Citations (0)

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References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Andersen J.S.,et al.Nature 426:570-574(2003).
Kleylein-Sohn J.,et al.Dev. Cell 13:190-202(2007).

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$ 293.00
Cat# AI15251
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