|Other Accession||NM_025009, NP_079285|
|Reactivity||Human, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Rabbit, Pig, Horse, Bovine, Dog|
|Alias Symbol||CEP4, KIAA0635|
|Other Names||Centrosomal protein of 135 kDa, Cep135, Centrosomal protein 4, CEP135, CEP4, KIAA0635|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CEP135 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CEP135 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles|
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Provided below are standard protocols that you may find useful for product applications.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Andersen J.S.,et al.Nature 426:570-574(2003).
Kleylein-Sohn J.,et al.Dev. Cell 13:190-202(2007).
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