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OST4 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - OST4 Antibody - C-terminal region AI15258

    WB Suggested Anti-OST4 Antibody Titration: 1.0 μg/ml
    Positive Control: MCF7 Whole Cell
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P0C6T2
Other Accession NM_001134693, NP_001128165
Reactivity Human, Mouse, Rat, Dog
Predicted Human, Mouse, Rat, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 4kDa
Additional Information
Gene ID 100128731
Alias Symbol DKFZp586A0722
Other Names Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4, OST4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-OST4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsOST4 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OST4 (HGNC:32483)
Function Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:31831667). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Specifically involved in maintaining stability of STT3A-containing OST complexes.
Cellular Location Endoplasmic reticulum. Endoplasmic reticulum membrane; Single- pass type III membrane protein. Note=The single transmembrane helix has a kink in the middle of the transmembrane span
Research Areas
Citations (0)
citation

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References

Hillier L.W.,et al.Nature 434:724-731(2005).
Gayen S.,et al.Biochem. Biophys. Res. Commun. 409:572-576(2011).

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$ 389.00
Cat# AI15258
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