SPG21 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9NZD8 |
Other Accession | NM_016630, NP_057714 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 35kDa |
Gene ID | 51324 |
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Alias Symbol | ACP33, BM-019, GL010, MASPARDIN, MAST |
Other Names | Maspardin, Acid cluster protein 33, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, Spastic paraplegia 21 protein, SPG21, ACP33 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SPG21 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | SPG21 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SPG21 |
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Synonyms | ACP33 |
Function | May play a role as a negative regulatory factor in CD4- dependent T-cell activation. |
Cellular Location | Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Partially localized in the cytosol but also accumulated on an intracellular vesicular compartment Colocalizes with CD4 on endosomal/trans-Golgi network |
Tissue Location | Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas Expressed in J.CaM1.6, HuT 78 and HeLa cell lines (at protein level) |
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Provided below are standard protocols that you may find useful for product applications.
References
Zeitlmann L.,et al.J. Biol. Chem. 276:9123-9132(2001).
Zhao M.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
Li Y.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:671-675(2006).
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