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SPG21 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - SPG21 Antibody - C-terminal region AI15262

    WB Suggested Anti-SPG21 Antibody Titration: 1.0 μg/ml
    Positive Control: 721_B Whole CellSPG21 is supported by BioGPS gene expression data to be expressed in 721_B
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9NZD8
Other Accession NM_016630, NP_057714
Reactivity Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 35kDa
Additional Information
Gene ID 51324
Alias Symbol ACP33, BM-019, GL010, MASPARDIN, MAST
Other Names Maspardin, Acid cluster protein 33, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, Spastic paraplegia 21 protein, SPG21, ACP33
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-SPG21 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSPG21 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPG21
Synonyms ACP33
Function May play a role as a negative regulatory factor in CD4- dependent T-cell activation.
Cellular Location Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Partially localized in the cytosol but also accumulated on an intracellular vesicular compartment Colocalizes with CD4 on endosomal/trans-Golgi network
Tissue Location Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas Expressed in J.CaM1.6, HuT 78 and HeLa cell lines (at protein level)
Research Areas
Citations (0)
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References

Zeitlmann L.,et al.J. Biol. Chem. 276:9123-9132(2001).
Zhao M.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
Li Y.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:671-675(2006).

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$ 389.00
Cat# AI15262
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