|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||PLEKHB1, EVT1, KPL1, PHR1, PHRET1,|
|Other Names||Pleckstrin homology domain-containing family B member 1, PH domain-containing family B member 1, Evectin-1, PH domain-containing protein in retina 1, PHRET1, Pleckstrin homology domain retinal protein 1, PLEKHB1, EVT1, KPL1, PHR1, PHRET1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-PKHB1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PKHB1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||EVT1, KPL1, PHR1, PHRET1|
|Function||Required for proper localization of retinogeniculate projections but not for eye-specific segregation.|
|Cellular Location||Membrane. Cytoplasm. Note=Localizes to the apical juxta- nuclear Golgi region of the cytoplasm (By similarity). Membrane- associated. Highly expressed in the outer segments of photoreceptor cells, both in rods and cones.|
|Tissue Location||Highly expressed in retina and brain. Levels are very low or not detectable in all other tissues tested|
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Provided below are standard protocols that you may find useful for product applications.
Xu S.,et al.J. Biol. Chem. 274:35676-35685(1999).
Andrews K.L.,et al.Exp. Lung Res. 26:257-271(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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