|Alias Symbol||TACR2, NK2R, NKNAR, TAC2R,|
|Other Names||Substance-K receptor, SKR, NK-2 receptor, NK-2R, Neurokinin A receptor, Tachykinin receptor 2, TACR2, NK2R, NKNAR, TAC2R|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 &mu, l of distilled water. Final Anti-NK2R antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||NK2R Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||NK2R, NKNAR, TAC2R|
|Function||This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Gerard N.P.,et al.J. Biol. Chem. 265:20455-20462(1990).
Gerard N.P.,et al.J. Biol. Chem. 266:1354-1354(1991).
Gerard N.P.,et al.Ann. N. Y. Acad. Sci. 632:389-390(1991).
Cyr C.,et al.Ann. N. Y. Acad. Sci. 632:426-427(1991).
Graham A.,et al.Biochem. Biophys. Res. Commun. 177:8-16(1991).
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