|Other Accession||NM_013353, NP_037485|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||DKFZp779I0852, SK-TMOD|
|Other Names||Tropomodulin-4, Skeletal muscle tropomodulin, Sk-Tmod, TMOD4|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-TMOD4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TMOD4 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.|
|Cellular Location||Cytoplasm, cytoskeleton. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574).|
|Tissue Location||Highly expressed in skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
Almenar-Queralt A.,et al.J. Biol. Chem. 274:28466-28475(1999).
Cox P.R.,et al.Genomics 63:97-107(2000).
Durling H.J.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Cox P.R.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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