|Other Accession||NM_025107, NP_079383|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||FLJ21269, MGC156309, MGC156310, MTLC|
|Other Names||Myc target protein 1, Myc target in myeloid cells protein 1, MYCT1, MTLC, MTMC1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-MYCT1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MYCT1 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).|
|Cellular Location||Nucleus. Note=Expressed in nuclei of hepatocellular carcinoma cell line BEL-7402 cells|
|Tissue Location||Down-regulated in gastric cancer tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Qiu G.-B.,et al.Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20:94-97(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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