|Other Accession||NM_020359, NP_065092|
|Reactivity||Human, Rat, Rabbit, Pig|
|Predicted||Human, Rat, Rabbit, Pig|
|Other Names||Phospholipid scramblase 2, PL scramblase 2, Ca(2+)-dependent phospholipid scramblase 2, PLSCR2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PLSCR2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PLSCR2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Expression of isoform 1 seems restricted to testis.|
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Provided below are standard protocols that you may find useful for product applications.
Wiedmer T.,et al.Biochim. Biophys. Acta 1467:244-253(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Rayala S.,et al.J. Biol. Chem. 289:13206-13218(2014).
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