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>   home   >   Products   >   Primary Antibodies   >   ANKFY1 Antibody - C-terminal region   

ANKFY1 Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - ANKFY1 Antibody - C-terminal region AI15383

    WB Suggested Anti-ANKFY1 Antibody Titration: 1.0 μg/ml
    Positive Control: 721_B Whole CellANKFY1 is supported by BioGPS gene expression data to be expressed in 721_B
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P2R3
Other Accession NM_020740, NP_065791
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Additional Information
Gene ID 51479
Alias Symbol ANKHZN, DKFZp686M19106, KIAA1255, ZFYVE14
Other Names Rabankyrin-5, Rank-5, Ankyrin repeat and FYVE domain-containing protein 1, Ankyrin repeats hooked to a zinc finger motif, ANKFY1, ANKHZN, KIAA1255
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ANKFY1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsANKFY1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ANKHZN, KIAA1255
Function Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extend in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the sucellular localization of the retromer complex in a EHD1- dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport.
Cellular Location Cytoplasm. Endosome membrane; Peripheral membrane protein. Early endosome. Note=Also associated with endosomal membranes. Localizes to macropinosomes
Tissue Location High expression in whole adult brain and intermediate expression in all other tissues and specific brain regions examined, including fetal brain
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$ 293.00
Cat# AI15383
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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