RASEF Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8IZ41 |
Other Accession | NM_152573, NP_689786 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 81kDa |
Gene ID | 158158 |
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Alias Symbol | FLJ31614, RAB45 |
Other Names | Ras and EF-hand domain-containing protein, Ras-related protein Rab-45, RASEF, RAB45 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-RASEF antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | RASEF Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RASEF |
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Synonyms | RAB45 |
Function | Binds predominantly GDP, and also GTP (PubMed:17448446). Acts as a dynein adapter protein that activates dynein-mediated transport and dynein-dynactin motility on microtubules (PubMed:30814157). |
Cellular Location | Cytoplasm, perinuclear region |
Tissue Location | Down-regulated in cutaneous melanoma cells but not in breast cancer cells. |
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Provided below are standard protocols that you may find useful for product applications.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
Joensson G.,et al.J. Natl. Cancer Inst. 97:1377-1382(2005).
Shintani M.,et al.Biochem. Biophys. Res. Commun. 357:661-667(2007).
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