|Other Accession||NM_024100, NP_077005|
|Reactivity||Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig|
|Predicted||Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig|
|Alias Symbol||MGC2436, R32184_1|
|Other Names||WD repeat-containing protein 18, WDR18|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-WDR18 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||WDR18 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.|
|Cellular Location||Nucleus, nucleoplasm. Cytoplasm. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions.|
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Provided below are standard protocols that you may find useful for product applications.
Grimwood J.,et al.Nature 428:529-535(2004).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Fanis P.,et al.Mol. Cell. Proteomics 11:1263-1273(2012).
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