|Other Accession||NM_153446, NP_703147|
|Alias Symbol||B4GALT, GALGT2, MGC142235, MGC142237|
|Other Names||Beta-1, 4 N-acetylgalactosaminyltransferase 2, 2.4.1.-, Sd(a) beta-1, 4-GalNAc transferase, UDP-GalNAc:Neu5Aca2-3Galb-R b1, 4-N-acetylgalactosaminyltransferase, B4GALNT2, GALGT2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-B4GALNT2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||B4GALNT2 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the synthesis of the Sd(a) antigen (Sia- alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues. Transfers a beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Widely expressed. Highly expressed in colon and to a lesser extent in kidney, stomach, ileum and rectum|
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Provided below are standard protocols that you may find useful for product applications.
Montiel M.D.,et al.Biochem. J. 373:369-379(2003).
Lo Presti L.,et al.J. Biochem. 134:675-682(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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