|Other Accession||NM_194313, NP_919289|
|Alias Symbol||C9orf48, bA571F15.4|
|Other Names||Kinesin-like protein KIF24, KIF24, C9orf48|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-KIF24 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||KIF24 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Primarily localizes to the mother centriole/basal body and is either absent at daughter centriole|
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Provided below are standard protocols that you may find useful for product applications.
Humphray S.J.,et al.Nature 429:369-374(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009).
Kobayashi T.,et al.Cell 145:914-925(2011).
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