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>   home   >   Products   >   Primary Antibodies   >   MYSM1 Antibody - C-terminal region   

MYSM1 Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - MYSM1 Antibody - C-terminal region AI15443

    Host: Rabbit
    Target Name: MYSM1
    Sample Tissue: Fetal Liver lysates
    Antibody Dilution: 1.0μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5VVJ2
Other Accession NM_001085487, NP_001078956
Reactivity Human, Rabbit, Dog
Predicted Human, Rabbit, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 91kDa
Additional Information
Gene ID 114803
Alias Symbol 2A-DUB, 2ADUB, DKFZp779J1554, DKFZp779J1721, KIAA1915, RP4-592A1.1
Other Names Histone H2A deubiquitinase MYSM1, 2A-DUB, 3.4.19.-, Myb-like, SWIRM and MPN domain-containing protein 1, MYSM1, KIAA1915
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-MYSM1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMYSM1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYSM1
Synonyms KIAA1915
Function Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00624, ECO:0000269|PubMed:17707232}
Citations (0)

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Nagase T.,et al.DNA Res. 8:179-187(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Gregory S.G.,et al.Nature 441:315-321(2006).
Zhu P.,et al.Mol. Cell 27:609-621(2007).

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$ 293.00
Cat# AI15443
(40 western blots)
Availability: 2-3 days
Bulk Size
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